4-(Dimethylamino)pyridine ReagentPlus®, ≥99%

4-(Dimethylamino)pyridine ReagentPlus®, ≥99%

-10% Off

Original price was: 10,500.00৳ .Current price is: 9,500.00৳ .

  • Brand:             Sigma
  • Catalog No.    107700-25G
  • Pack Size:      25G

  • Properties

    grade

    reagent grade

    Quality Segment

    200

    product line

    ReagentPlus®

    assay

    ≥99%

    form

    chips, crystalline powder, flakes

    concentration

    ≤100%

    pH

    (10,23 at -0,1 g/l at 22  °C)

    bp

    162 °C

    mp

    108-110 °C (lit.)

    solubility

    H2O: 50 mg/mL

    functional group

    amine

    storage temp.

    room temp

    SMILES string

    CN(C)c1ccncc1

    InChI

    1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

    InChI key

    VHYFNPMBLIVWCW-UHFFFAOYSA-N

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Description

Description

General description

4-(Dimethylamino)pyridine (DMAP) is a highly versatile nucleophilic catalyst for acylation reactions and esterifications. It is also employed in various organic transformations like Baylis-Hillman reaction, Dakin-West reaction, protection of amines, C-acylations, silylations, applications in natural products chemistry, and many others.

Application

4-(Dimethylamino)pyridine can be used as a catalyst:

  • To synthesize 3,5-disubstituted 2,6-dicyanoaniline by reacting malononitrile, aldehydes, and β-nitroolefins.
  • For the acylation of alcohols with acid anhydrides under auxiliary base- and solvent-free conditions to synthesize corresponding esters.
  • In Baylis-Hillman reaction to form carbon-carbon bond by the coupling of an activated alkene with an aldehyde or ketone.
A highly efficient catalyst for acylation reactions

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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4-(Dimethylamino)pyridine ReagentPlus®, ≥99%

Original price was: 10,500.00৳ .Current price is: 9,500.00৳ .